Healthy hair is maintained through regeneration of hair follicles by activation of multipotent epithelial stem cells residing in the outer hair root sheath. The hair cycle is comprised of a finite period of hair growth (anagen phase), a brief regression phase (catagen phase), and a resting period (telogen phase). It is regulated by sensory neurons, cytokines, growth factors (GFs), and hormones. The growth of new hair requires re-entry into the anagen phase. Phospholipids possess potent growth effects on murine hair epithelial cells, thereby inducing early telogen-to-anagen phase conversion, promoting cell growth, and elongating shafts in hair follicles. Phospholipids also combine with the proteins (keratin) of the hair and simultaneously fixate the fat-soluble hair care substances carried along leaving hair supple and conditioned.