The lipophilic fatty acids and hydrophilic phosphoric acid based esters together contribute an amphiphilic character. They are bipolar and act as an emulsifying agent.

  • Natural emulsifiers.
  • Have self emulsifying property.
  • Far better tolerated than ethoxylated emulsifiers or any other alternatives.
  • They are multifunctional and can be used in both o/w and w/o emulsions.
  • Form stable emulsions.
Phospholipids For Pharmaceuticals

Liposomal Agents

Phospholipids when hydrated have a unique property of self assembling into vesicles. These vesicles known as LIPOSOMES are promising systems for drug delivery and can be unilamellar (single phospholipid bilayer) or multilamellar (two or more phospholipid bilayers). They can encapsulate both, drugs and phyto-actives or phytonutrients.

They are highly biocompatible, biodegradable with no toxicity & high aptitude to entrap both hydrophilic and hydrophobic drugs and have site specific drug delivery.


  • Phospholipids improve skin condition by increasing hydration level of skin and integrity of the stratum corneum.
  • They do not disrupt the skin defence mechanism and structure.
  • Enhances penetration of individual lipid components into stratum corneum and subsequent alteration of the intercellular lipid matrix within the skin.
  • Improves the stability of unstable compounds.
  • Localized skin delivery

Targeted Drug Delivery

  • Smart drug delivery system.
  • Increases accumulation of liposomal formulations in the desired cells and tissues, by using the targeted liposomes including surface-attached ligands such as; antibodies, folates, peptides and transferrin that are capable of recognizing and binding to the desired diseased cells, leaving healthy cells intact.
  • Beneficial for stabilizing therapeutic compounds, overcoming obstacles to cellular and tissue uptake and improving biodistribution of compounds to target sites in vivo.


  • Phosphatidylcholine (PC) is involved in reverse cholesterol transport by effecting Lecithin cholesterol acyltransferase.
  • Lecithin cholesterol acyltransferase (LCAT) is an enzyme made in the liver which catalyzes the uptake of free cholesterol from the plasma into the lipoprotein particle.
  • LCAT converts immature disc-shaped HDLs to mature, large round HDL.
    HDL particles get bigger as cholesterol is brought into its core. In fact, measurement of HDL sizes is an indirect way of assessing the degree of reverse cholesterol transport.
  • PC allows the ALCAT enzyme to put more cholesterol into HDL particles. Doing this clears more non-HDL cholesterol from the circulation. Purified forms of PC have been shown to work both orally and intravenously to improve cholesterol numbers. Intravenous injections of PC are found to be effective in reducing symptoms of angina pectoris.


It is the latest range of lipo-sculpting (removing) fat accumulations i.e. to reduce or eliminate unwanted localized accumulated fats. It is non-surgical, relatively painless injection technique.

  • Mesotherapy will replenish the PC in adipose cell membrane.
  • PC penetrates the adipocytes and is then, due to the impact of phospholipase D, hydrolyzed to phosphoric acid and choline.
  • Cholines act as emulsifiers and phosphoric acid triggers the activation of protein kinase C (PKC).
  • The latter has the effect that lipolytic lipases – assisted by hormone sensitive lipases hydrolyze triglycerides to become fatty acids and glycerine. They are then transported to the liver and eliminated as bile acid.